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Saccharomyces cerevisiae (S288c)

CDC5

MSD2, PKX2, polo kinase CDC5, L000000245, YMR001C

Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate

Kinome Project (Sc)

GO Process (6)

GO Function (2)

GO Component (3)

Gene Ontology Biological Process

positive regulation of spindle pole body separation [IGI, IMP]

protein localization [IMP]

protein phosphorylation [IDA, IMP]

resolution of meiotic recombination intermediates [IMP]

spindle assembly involved in meiosis [IMP]

synaptonemal complex disassembly [IGI]

Gene Ontology Molecular Function

enzyme activator activity [IDA]
protein kinase activity [IDA, IMP]

Gene Ontology Cellular Component

cellular bud neck [IDA]

spindle pole [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35171

559292

Interactors 229
Interactions 469
Network
PTM Sites 23