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Saccharomyces cerevisiae (S288c)

SGV1

BUR1, cyclin-dependent serine/threonine protein kinase SGV1, L000001878, YPR161C

Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins

Kinome Project (Sc)

GO Process (4)

GO Function (2)

GO Component (2)

Gene Ontology Biological Process

phosphorylation of RNA polymerase II C-terminal domain [IDA, IMP, IPI]

positive regulation of histone H3-K4 methylation [IMP]

protein phosphorylation [IDA, IPI]

transcription, DNA-templated [IDA, IMP, IPI]

Gene Ontology Molecular Function

RNA polymerase II carboxy-terminal domain kinase activity [IDA]
cyclin-dependent protein serine/threonine kinase activity [IDA]

Gene Ontology Cellular Component

cyclin-dependent protein kinase holoenzyme complex [IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36334

559292

Interactors 1,143
Interactions 1,404
Network
PTM Sites 9