BAIT
HEN1
CORYMBOSA 2, CRM2, HUA ENHANCER 1, T13K14.70, T13K14_70, AT4G20910
small RNA 2'-O-methyltransferase
GO Process (8)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- leaf proximal/distal pattern formation [IMP]
- leaf vascular tissue pattern formation [IMP]
- mRNA cleavage involved in gene silencing by miRNA [IMP]
- production of miRNAs involved in gene silencing by miRNA [IMP, NAS]
- production of siRNA involved in RNA interference [IGI, IMP]
- regulation of flower development [IMP]
- specification of floral organ identity [IMP]
- virus induced gene silencing [IMP]
Gene Ontology Molecular Function
Arabidopsis thaliana (Columbia)
PREY
MIR173
microRNA173, AT3G23125
ncRNA
GO Process (1)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Arabidopsis thaliana (Columbia)
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
Mechanistic insights into small RNA recognition and modification by the HEN1 methyltransferase.
The HEN1 methyltransferase from Arabidopsis thaliana modifies the 3'-terminal nucleotides of small regulatory RNAs. Although it is one of the best characterized members of the 2'-O-methyltransferase family, many aspects of its interactions with the cofactor and substrate RNA remained unresolved. To better understand the substrate interactions and contributions of individual steps during HEN1 catalysis, we studied the binding and methylation ... [more]
Biochem. J. Jul. 15, 2013; 453(2);281-90 [Pubmed: 23621770]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| HEN1 MIR173 | Protein-RNA Protein-RNA An interaction is detected between and protein and an RNA in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID