BAIT
WDR92
WD repeat domain 92
GO Process (1)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
PPP3CB
CALNA2, CALNB, CNA2, PP2Bbeta, RP11-345K20.1
protein phosphatase 3, catalytic subunit, beta isozyme
GO Process (21)
GO Function (9)
GO Component (4)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- T cell activation [TAS]
- T cell proliferation [NAS]
- axon extension [TAS]
- calcineurin-NFAT signaling cascade [IDA]
- calcium ion-dependent exocytosis [ISS]
- cellular response to drug [IDA]
- dephosphorylation [TAS]
- innate immune response [TAS]
- learning [TAS]
- memory [TAS]
- positive regulation of NFAT protein import into nucleus [IDA]
- positive regulation of insulin secretion involved in cellular response to glucose stimulus [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [NAS]
- protein dephosphorylation [ISS]
- protein phosphorylation [ISS]
- regulation of insulin secretion [ISS]
- regulation of synaptic plasticity [TAS]
- signal transduction [NAS]
- social behavior [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A high-throughput approach for measuring temporal changes in the interactome.
Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]
Nat. Methods Sep. 01, 2012; 9(9);907-9 [Pubmed: 22863883]
Throughput
- High Throughput
Ontology Terms
- cell line: hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID