BAIT

BKRF1

EBNA-1 protein
GO Process (0)
GO Function (0)
GO Component (0)
Human Herpesvirus 4
PREY

PI4KB

NPIK, PI4K-BETA, PI4K92, PI4KBETA, PI4KIIIBETA, PIK4CB, RP11-126K1.4
phosphatidylinositol 4-kinase, catalytic, beta
Cell Cycle - Mitotic Spindle Assembly Project
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency.

Wang Y, Du S, Zhu C, Wang C, Yu N, Lin Z, Gan J, Guo Y, Huang X, He Y, Robertson E, Qu D, Wei F, Cai Q

Latent Epstein-Barr virus (EBV) infection is strongly associated with several malignancies, including B-cell lymphomas and epithelial tumors. EBNA1 is a key antigen expressed in all EBV-associated tumors during latency that is required for maintenance of the EBV episome DNA and the regulation of viral gene transcription. However, the mechanism utilized by EBV to maintain latent infection at the levels of ... [more]

PLoS Pathog Dec. 01, 2019; 16(3);e1008447 [Pubmed: 32176739]

Throughput

  • High Throughput

Curated By

  • BioGRID