Homo sapiens
ALOX12
12-LOX, 12S-LOX, LOG12
arachidonate 12-lipoxygenase
GO Process (23)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- arachidonic acid metabolic process [IDA, ISS, TAS]
- cellular component movement [IMP]
- establishment of skin barrier [ISS]
- fatty acid oxidation [IMP]
- hepoxilin biosynthetic process [ISS]
- hepoxilin metabolic process [TAS]
- leukotriene A4 metabolic process [IDA]
- linoleic acid metabolic process [IDA]
- lipoxin A4 biosynthetic process [IDA]
- lipoxin B4 biosynthetic process [IDA]
- lipoxin metabolic process [TAS]
- lipoxygenase pathway [IDA, TAS]
- negative regulation of apoptotic process [IMP, ISS]
- negative regulation of muscle cell apoptotic process [IMP]
- negative regulation of platelet aggregation [ISS]
- positive regulation of angiogenesis [IMP]
- positive regulation of cell adhesion [IMP]
- positive regulation of cell growth [IMP]
- positive regulation of cell migration [IMP]
- positive regulation of cell proliferation [IMP, ISS]
- reactive oxygen species metabolic process [NAS]
- small molecule metabolic process [TAS]
- superoxide anion generation [NAS]
Gene Ontology Molecular Function- arachidonate 12-lipoxygenase activity [IDA, TAS]
- hepoxilin A3 synthase activity [TAS]
- hepoxilin-epoxide hydrolase activity [ISS]
- linoleate 13S-lipoxygenase activity [IDA]
- oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [TAS]
- protein binding [IPI]
- arachidonate 12-lipoxygenase activity [IDA, TAS]
- hepoxilin A3 synthase activity [TAS]
- hepoxilin-epoxide hydrolase activity [ISS]
- linoleate 13S-lipoxygenase activity [IDA]
- oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [TAS]
- protein binding [IPI]
Download Curated Data for this Protein
106740
9606
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- Interactors 16
- Interactions 21
- Network
- PTM Sites 1