Homo sapiens
AKR1C3
DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS
aldo-keto reductase family 1, member C3
GO Process (37)
GO Function (13)
GO Component (5)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IDA]
- arachidonic acid metabolic process [TAS]
- cellular response to cadmium ion [IDA]
- cellular response to calcium ion [IDA]
- cellular response to corticosteroid stimulus [IDA]
- cellular response to jasmonic acid stimulus [IDA]
- cellular response to prostaglandin D stimulus [IDA]
- cellular response to prostaglandin stimulus [IDA]
- cellular response to reactive oxygen species [IDA]
- cellular response to starvation [IEP]
- cyclooxygenase pathway [TAS]
- daunorubicin metabolic process [IMP]
- doxorubicin metabolic process [IMP]
- farnesol catabolic process [IDA]
- keratinocyte differentiation [IEP]
- male gonad development [IEP]
- multicellular organismal macromolecule metabolic process [IEP]
- negative regulation of retinoic acid biosynthetic process [IDA]
- oxidation-reduction process [IDA, TAS]
- phototransduction, visible light [TAS]
- positive regulation of cell death [IDA]
- positive regulation of cell proliferation [IDA, IMP]
- positive regulation of endothelial cell apoptotic process [IDA]
- positive regulation of protein kinase B signaling [IDA]
- positive regulation of reactive oxygen species metabolic process [IDA]
- progesterone metabolic process [IDA]
- prostaglandin metabolic process [IEP, TAS]
- protein import into nucleus, translocation [IDA]
- regulation of retinoic acid receptor signaling pathway [IDA]
- regulation of testosterone biosynthetic process [IMP]
- renal absorption [NAS]
- response to nutrient [IEP]
- retinal metabolic process [IDA]
- retinoid metabolic process [TAS]
- small molecule metabolic process [TAS]
- steroid metabolic process [IEP]
- testosterone biosynthetic process [IMP]
Gene Ontology Molecular Function- 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [IDA]
- alditol:NADP+ 1-oxidoreductase activity [IDA]
- aldo-keto reductase (NADP) activity [TAS]
- androsterone dehydrogenase activity [IDA]
- delta4-3-oxosteroid 5beta-reductase activity [IDA]
- dihydrotestosterone 17-beta-dehydrogenase activity [IDA]
- geranylgeranyl reductase activity [IDA]
- ketoreductase activity [IDA]
- ketosteroid monooxygenase activity [IDA]
- oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [IDA]
- phenanthrene 9,10-monooxygenase activity [IDA]
- retinal dehydrogenase activity [IDA]
- retinol dehydrogenase activity [IDA]
- 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [IDA]
- alditol:NADP+ 1-oxidoreductase activity [IDA]
- aldo-keto reductase (NADP) activity [TAS]
- androsterone dehydrogenase activity [IDA]
- delta4-3-oxosteroid 5beta-reductase activity [IDA]
- dihydrotestosterone 17-beta-dehydrogenase activity [IDA]
- geranylgeranyl reductase activity [IDA]
- ketoreductase activity [IDA]
- ketosteroid monooxygenase activity [IDA]
- oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [IDA]
- phenanthrene 9,10-monooxygenase activity [IDA]
- retinal dehydrogenase activity [IDA]
- retinol dehydrogenase activity [IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
114196
9606
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- Interactors 55
- Interactions 67
- Chemical Interactions 21
- Network
- PTM Sites 44