Saccharomyces cerevisiae (S288c)


PYK1, pyruvate kinase CDC19, L000000258, YAL038W
Pyruvate kinase; functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration; regulated via allosteric activation by fructose bisphosphate; CDC19 has a paralog, PYK2, that arose from the whole genome duplication
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  • Interactors 321
  • Interactions 377
  • Network
  • PTM Sites 63