Saccharomyces cerevisiae (S288c)


PPH2, phosphoprotein phosphatase 2A catalytic subunit PPH22, L000001473, YDL188C
Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; protein abundance increases in response to DNA replication stress; PPH22 has a paralog, PPH21, that arose from the whole genome duplication
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  • Interactors 162
  • Interactions 238
  • Network
  • PTM Sites 5