Saccharomyces cerevisiae (S288c)

GCN2

AAS1, AAS102, NDR2, serine/threonine-protein kinase GCN2, L000000681, YDR283C

Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control

Kinome Project (Sc)

GO Process (5)

GO Function (2)

GO Component (1)

Gene Ontology Biological Process

DNA damage checkpoint [IMP]

cellular amino acid biosynthetic process [IMP]

chronological cell aging [IMP]

protein phosphorylation [IDA]

regulation of translational initiation [IDA]

Gene Ontology Molecular Function

eukaryotic translation initiation factor 2alpha kinase activity [IDA]
protein serine/threonine kinase activity [IDA, IMP]

Gene Ontology Cellular Component

cytosolic ribosome [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32336

559292

Interactors 257
Interactions 454
Network
PTM Sites 15

Result Summary

GCN2

Gene Ontology Biological Process

Gene Ontology Molecular Function

eukaryotic translation initiation factor 2alpha kinase activity [IDA]protein serine/threonine kinase activity [IDA, IMP]

Gene Ontology Cellular Component

eukaryotic translation initiation factor 2alpha kinase activity [IDA]
protein serine/threonine kinase activity [IDA, IMP]