Saccharomyces cerevisiae (S288c)


protein kinase PKP2, YGL059W
Mitochondrial protein kinase; negatively regulates activity of the pyruvate dehydrogenase complex by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp1p and phosphatases Ptc5p and Ptc6p; relocalizes from mitochondrion to cytoplasm upon DNA replication stress
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  • Interactors 150
  • Interactions 163
  • Network
  • PTM Sites 6