Saccharomyces cerevisiae (S288c)

ALK1

protein kinase ALK1, L000002852, YGL021W
Protein kinase; along with its paralog, ALK2, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of cell polarity factors in mitosis, proper localization of formins and polarity factors, and survival in cells that activate spindle assembly checkpoint; phosphorylated in response to DNA damage; ALK1 has a paralog, ALK2, that arose from the whole genome duplication; similar to mammalian haspins
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  • Interactors 55
  • Interactions 57
  • Network
  • PTM Sites 41