Saccharomyces cerevisiae (S288c)

PAN1

DIM2, MDP3, MIP3, L000001335, YIR006C
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p; associates with actin patches on cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates Arp2/3 complex in vitro; phosphorylation of Thr-1225 is regulated by MAPK Hog1p in response to osmotic stress; previously thought to be a subunit of poly(A) ribonuclease
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  • Interactors 651
  • Interactions 927
  • Network
  • PTM Sites 48