Saccharomyces cerevisiae (S288c)

IPL1

PAC15, aurora kinase, L000000871, YPL209C
Aurora kinase of conserved chromosomal passenger complex; mediates release on mono-oriented kinetochores from microtubules in meiosis I, also release of kinetochores from cluster at SPBs at meiosis exit; helps maintain condensed chromosomes during anaphase, early telophase; required for SPB cohesion and prevention of multipolar spindle formation; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest
PHO
KIN

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB
Download 704 Published Interactions For This Protein
35976
559292
  • Stats & Options
Switch View:
  • Interactors (504)
  • Interactions (704)
  • Network
  • PTM Sites (6)