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Saccharomyces cerevisiae (S288c)

CLB2

B-type cyclin CLB2, L000000350, YPR119W

B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome; CLB2 has a paralog, CLB1, that arose from the whole genome duplication

Kinome Project (Sc)

GO Process (5)

GO Function (2)

GO Component (5)

Gene Ontology Biological Process

G2/M transition of mitotic cell cycle [IEP, IMP]

negative regulation of protein dephosphorylation [IDA]

positive regulation of spindle pole body separation [IGI]

regulation of cyclin-dependent protein serine/threonine kinase activity [IMP]

regulation of mitotic spindle elongation [IMP]

Gene Ontology Molecular Function

cyclin-dependent protein serine/threonine kinase regulator activity [IDA, IMP]
protein binding [IPI]

Gene Ontology Cellular Component

cellular bud neck [IDA]

cytoplasm [IDA, IMP, ISS]

spindle pole body [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36287

559292

Interactors 305
Interactions 697
Network
PTM Sites 6