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Saccharomyces cerevisiae (S288c)

PTC2

type 2C protein phosphatase PTC2, L000003403, YER089C

Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; inactivates the DNA damage checkpoint; PTC2 has a paralog, PTC3, that arose from the whole genome duplication

Kinome Project (Sc)

GO Process (5)

GO Function (1)

GO Component (2)

Gene Ontology Biological Process

DNA damage checkpoint [IGI]

endoplasmic reticulum unfolded protein response [IMP, IPI]

inactivation of MAPK activity involved in osmosensory signaling pathway [IDA, IGI, IMP]

protein dephosphorylation [IDA]

regulation of cyclin-dependent protein serine/threonine kinase activity [IMP, IPI]

Gene Ontology Molecular Function

protein serine/threonine phosphatase activity [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36834

559292

Interactors 218
Interactions 306
Network
PTM Sites 11