BAIT
GOLGA2
GM130, RP11-395P17.5
golgin A2
GO Process (2)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PID1
NYGGF4, P-CLI1, PCLI1, HMFN2073
phosphotyrosine interaction domain containing 1
GO Process (22)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
- cellular response to cytokine stimulus [ISS]
- cellular response to fatty acid [ISS]
- cellular response to interleukin-6 [ISS]
- cellular response to tumor necrosis factor [ISS, NAS]
- energy reserve metabolic process [IC]
- fat cell differentiation [IDA]
- mitochondrion morphogenesis [IMP]
- negative regulation of ATP biosynthetic process [IMP]
- negative regulation of establishment of protein localization to plasma membrane [IDA]
- negative regulation of glucose import in response to insulin stimulus [IDA]
- negative regulation of insulin receptor signaling pathway [IDA]
- negative regulation of mitochondrial DNA replication [IMP]
- negative regulation of protein phosphorylation [IDA]
- positive regulation of ATP biosynthetic process [ISS]
- positive regulation of fat cell proliferation [IDA]
- positive regulation of gene expression [IMP]
- positive regulation of reactive oxygen species metabolic process [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of G1/S transition of mitotic cell cycle [IDA]
- regulation of mitochondrial fusion [IC]
- regulation of mitochondrial membrane potential [ISS, TAS]
- regulation of reactive oxygen species metabolic process [ISS]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A proteome-scale map of the human interactome network.
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ?30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently ... [more]
Cell Nov. 20, 2014; 159(5);1212-26 [Pubmed: 25416956]
Throughput
- High Throughput
Curated By
- BioGRID