SKIL
Gene Ontology Biological Process
- cell cycle arrest [ISS]
- gene expression [TAS]
- negative regulation of cell differentiation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA, TAS]
- negative regulation of transforming growth factor beta receptor signaling pathway [IDA]
- positive regulation of axonogenesis [IMP]
- protein heterotrimerization [IDA]
- protein homotrimerization [IDA]
- regulation of apoptotic process [IBA, ISS]
- response to antibiotic [IEP]
- response to growth factor [IDA]
- skeletal muscle tissue development [IDA]
- transcription initiation from RNA polymerase II promoter [TAS]
- transcription, DNA-templated [TAS]
- transforming growth factor beta receptor signaling pathway [TAS]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- SMAD binding [IPI]
- chromatin binding [ISS]
- protein binding [IPI]
- protein complex binding [IDA]
- protein domain specific binding [IPI]
- transcription corepressor activity [IDA]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- SMAD binding [IPI]
- chromatin binding [ISS]
- protein binding [IPI]
- protein complex binding [IDA]
- protein domain specific binding [IPI]
- transcription corepressor activity [IDA]
Gene Ontology Cellular Component
VPS28
Gene Ontology Biological Process
- endosomal transport [TAS]
- intracellular transport of virus [TAS]
- membrane organization [TAS]
- negative regulation of protein ubiquitination [IDA]
- protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [IBA]
- ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [IC, IMP]
- viral life cycle [TAS]
- viral process [TAS]
- viral protein processing [TAS]
- virion assembly [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A proteome-scale map of the human interactome network.
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ?30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| VPS28 SKIL | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
| VPS28 SKIL | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID