Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

TRIP6 transcriptional co-activator is a novel substrate of AMP-activated protein kinase.

Solaz-Fuster MC, Gimeno-Alcaniz JV, Casado M, Sanz P

AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that acts as a sensor of cellular energy charge. Once activated it switches on catabolic pathways and switches off many ATP-consuming processes (anabolic pathways) to preserve the energy status of the cell. In order to identify new targets of AMPK action we have performed a two-hybrid screening of a human pancreas ... [more]

Cell. Signal. Oct. 01, 2006; 18(10);1702-12 [Pubmed: 16624523]

Throughput

Low Throughput

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
NEDD9 TRIP6	Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.	Rolland T (2014)	High	-	BioGRID	-
TRIP6 NEDD9	Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.	Yi J (2002)	Low	-	BioGRID	-

Curated By

BioGRID

Interaction Summary

TRIP6

Gene Ontology Biological Process

Gene Ontology Molecular Function

interleukin-1 receptor binding [IDA]kinase binding [IPI]poly(A) RNA binding [IDA]protein binding [IPI]thyroid hormone receptor binding [NAS]

Gene Ontology Cellular Component

NEDD9