Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers.

Yi J, Kloeker S, Jensen CC, Bockholt S, Honda H, Hirai H, Beckerle MC

Integrin binding to extracellular matrix proteins induces formation of signaling complexes at focal adhesions. Zyxin co-localizes with integrins at sites of cell-substratum adhesion and is postulated to serve as a docking site for the assembly of multimeric protein complexes involved in regulating cell motility. Recently, we identified a new member of the zyxin family called TRIP6. TRIP6 is localized at ... [more]

J. Biol. Chem. Mar. 15, 2002; 277(11);9580-9 [Pubmed: 11782456]

Throughput

Low Throughput

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
NEDD9 TRIP6	Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.	Rolland T (2014)	High	-	BioGRID	-
TRIP6 NEDD9	Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.	Solaz-Fuster MC (2006)	Low	-	BioGRID	-

Curated By

BioGRID

Interaction Summary

TRIP6

Gene Ontology Biological Process

Gene Ontology Molecular Function

interleukin-1 receptor binding [IDA]kinase binding [IPI]poly(A) RNA binding [IDA]protein binding [IPI]thyroid hormone receptor binding [NAS]

Gene Ontology Cellular Component

NEDD9