CAMK1D
Gene Ontology Biological Process
- positive regulation of CREB transcription factor activity [IDA]
- positive regulation of neuron projection development [ISS]
- positive regulation of neutrophil chemotaxis [ISS]
- positive regulation of phagocytosis [IMP]
- positive regulation of respiratory burst [IMP]
- regulation of dendrite development [IMP]
- regulation of granulocyte chemotaxis [IMP]
CAMK1
Gene Ontology Biological Process
- positive regulation of dendritic spine development [IMP]
- positive regulation of muscle cell differentiation [IMP]
- positive regulation of neuron projection development [IDA]
- positive regulation of protein serine/threonine kinase activity [IDA]
- positive regulation of synapse structural plasticity [IMP]
- protein phosphorylation [IDA]
- regulation of muscle cell differentiation [IDA]
- regulation of protein binding [IDA]
- regulation of protein localization [IDA]
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network: A Systematic Exploration of the Human Interactome.
Protein interactions form a network whose structure drives cellular function and whose organization informs biological inquiry. Using high-throughput affinity-purification mass spectrometry, we identify interacting partners for 2,594 human proteins in HEK293T cells. The resulting network (BioPlex) contains 23,744 interactions among 7,668 proteins with 86% previously undocumented. BioPlex accurately depicts known complexes, attaining 80%-100% coverage for most CORUM complexes. The network ... [more]
Quantitative Score
- 0.999999998 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 1.0 HEK 293T cells CompPASS score = 0.999999998, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 2.0 (PMID: 28514442) and BioPlex 3.0 (PMID: 33961781). Only scores from within BioPlex 1.0 (PMID: 26186194) should be compared directly.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CAMK1 CAMK1D | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 5814 | BioGRID | 3483936 | |
| CAMK1D CAMK1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 5304 | BioGRID | 3484805 | |
| CAMK1D CAMK1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 2217957 | |
| CAMK1D CAMK1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3128725 |
Curated By
- BioGRID