BAIT
CDKN2D
INK4D, p19, p19-INK4D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
GO Process (15)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- DNA synthesis involved in DNA repair [IMP]
- G1/S transition of mitotic cell cycle [IDA]
- autophagic cell death [IMP]
- cell cycle arrest [IDA]
- mitotic cell cycle [TAS]
- negative regulation of cell growth [IDA]
- negative regulation of cell proliferation [IDA]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- negative regulation of phosphorylation [IDA]
- negative regulation of protein serine/threonine kinase activity [IDA]
- regulation of cyclin-dependent protein serine/threonine kinase activity [IDA]
- response to UV [IMP]
- response to retinoic acid [IMP]
- response to vitamin D [IMP]
Gene Ontology Molecular Function
Homo sapiens
PREY
TBC1D17
TBC1 domain family, member 17
GO Process (2)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Towards a proteome-scale map of the human protein-protein interaction network.
Systematic mapping of protein-protein interactions, or 'interactome' mapping, was initiated in model organisms, starting with defined biological processes and then expanding to the scale of the proteome. Although far from complete, such maps have revealed global topological and dynamic features of interactome networks that relate to known biological properties, suggesting that a human interactome map will provide insight into development ... [more]
Nature Oct. 20, 2005; 437(7062);1173-8 [Pubmed: 16189514]
Throughput
- High Throughput
Curated By
- BioGRID