BAIT

LGALS3

CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2
lectin, galactoside-binding, soluble, 3
Homo sapiens
PREY

TMPO

CMD1T, LAP2, LEMD4, PRO0868, TP
thymopoietin
GO Process (0)
GO Function (2)
GO Component (5)

Gene Ontology Molecular Function

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Characterization of LGALS3 (galectin-3) as a player in DNA damage response.

Carvalho RS, Fernandes VC, Nepomuceno TC, Rodrigues DC, Woods NT, Suarez-Kurtz G, Chammas R, Monteiro AN, Carvalho MA

DNA damage repair (DDR) is an orchestrated process encompassing the injury detection to its complete resolution. DNA double-strand break lesions are repaired mainly by two distinct mechanisms: the error-free homologous recombination (HR) and the error-prone non-homologous end-joining. Galectin-3 (GAL3) is the unique member of the chimeric galectins subfamily and is reported to be involved in several cancer development and progression ... [more]

Cancer Biol. Ther. Jul. 01, 2014; 15(7);840-50 [Pubmed: 24755837]

Throughput

  • Low Throughput

Curated By

  • BioGRID