BAIT
OFD1
71-7A, CXorf5, JBTS10, RP23, SGBS2
oral-facial-digital syndrome 1
GO Process (7)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RAB6A
RAB6
RAB6A, member RAS oncogene family
GO Process (10)
GO Function (6)
GO Component (6)
Gene Ontology Biological Process
- GTP catabolic process [IDA, TAS]
- Rab protein signal transduction [IBA]
- antigen processing and presentation [IMP]
- early endosome to Golgi transport [IMP]
- minus-end-directed organelle transport along microtubule [TAS]
- peptidyl-cysteine methylation [IDA]
- protein localization to Golgi apparatus [IDA]
- protein targeting to Golgi [IDA]
- retrograde transport, endosome to Golgi [IBA]
- retrograde vesicle-mediated transport, Golgi to ER [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID