BAIT
TCTN3
C10orf61, JBTS18, OFD4, TECT3, RP11-7D5.3
tectonic family member 3
GO Process (2)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
NDUFS1
CI-75Kd, CI-75k, PRO1304
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
GO Process (9)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- ATP metabolic process [IMP]
- apoptotic mitochondrial changes [IDA]
- cellular metabolic process [TAS]
- cellular respiration [IMP]
- mitochondrial electron transport, NADH to ubiquinone [NAS]
- reactive oxygen species metabolic process [IMP]
- regulation of mitochondrial membrane potential [IMP]
- respiratory electron transport chain [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of critical cellular functions. Here, we use proximity-dependent biotinylation (BioID) to map the centrosome-cilium interface; with 58 bait proteins we generate a protein topology network comprising >7,000 interactions. Analysis of interaction profiles coupled with high resolution phenotypic profiling implicates a ... [more]
Cell Dec. 03, 2015; 163(6);1484-99 [Pubmed: 26638075]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID