BUD2
Gene Ontology Biological Process
- axial cellular bud site selection [IMP]
- bipolar cellular bud site selection [IMP]
- establishment or maintenance of cell polarity [IMP]
- filamentous growth [IMP]
- invasive filamentous growth [IMP]
- mitotic spindle orientation checkpoint [IMP]
- negative regulation of Ras protein signal transduction [IBA]
- positive regulation of Ras GTPase activity [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CLN2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map for cell polarity development.
Many genes required for cell polarity development in budding yeast have been identified and arranged into a functional hierarchy. Core elements of the hierarchy are widely conserved, underlying cell polarity development in diverse eukaryotes. To enumerate more fully the protein-protein interactions that mediate cell polarity development, and to uncover novel mechanisms that coordinate the numerous events involved, we carried out ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
CLN2 BUD2 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.6932 | BioGRID | 2446137 | |
CLN2 BUD2 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 352125 | |
CLN2 BUD2 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 205735 |
Curated By
- BioGRID