TPM1
Gene Ontology Biological Process
- cardiac muscle contraction [IMP]
- cellular component movement [TAS]
- cellular response to reactive oxygen species [IEP]
- cytoskeleton organization [TAS]
- muscle contraction [TAS]
- muscle filament sliding [ISS, TAS]
- negative regulation of cell migration [ISS]
- positive regulation of ATPase activity [ISS]
- positive regulation of cell adhesion [ISS]
- positive regulation of heart rate by epinephrine [ISS]
- positive regulation of stress fiber assembly [ISS]
- regulation of heart contraction [TAS]
- regulation of muscle contraction [TAS]
- ruffle organization [ISS]
- sarcomere organization [IMP]
- ventricular cardiac muscle tissue morphogenesis [IMP]
- wound healing [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Next-generation sequencing to generate interactome datasets.
Next-generation sequencing has not been applied to protein-protein interactome network mapping so far because the association between the members of each interacting pair would not be maintained in en masse sequencing. We describe a massively parallel interactome-mapping pipeline, Stitch-seq, that combines PCR stitching with next-generation sequencing and used it to generate a new human interactome dataset. Stitch-seq is applicable to ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
TNNT1 TPM1 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
TNNT1 TPM1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
TPM1 TNNT1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID