BAIT
AHSA1
AHA1, C14orf3, p38, HSPC322
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PRPF19
NMP200, PRP19, PSO4, SNEV, UBOX4, hPSO4
pre-mRNA processing factor 19
GO Process (10)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- cellular protein localization [IMP]
- double-strand break repair via nonhomologous end joining [IMP]
- generation of catalytic spliceosome for first transesterification step [IBA]
- mRNA splicing, via spliceosome [IC, IDA]
- proteasomal protein catabolic process [IMP]
- protein K63-linked ubiquitination [IMP]
- protein polyubiquitination [IDA]
- signal transduction involved in DNA damage checkpoint [IMP]
- spliceosomal complex assembly [IMP]
- spliceosomal tri-snRNP complex assembly [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The dynamic interactome of human Aha1 upon Y223 phosphorylation.
Heat Shock Protein 90 (Hsp90) is an essential chaperone that supports the function of a wide range of signaling molecules. Hsp90 binds to a suite of co-chaperone proteins that regulate Hsp90 function through alteration of intrinsic ATPase activity. Several studies have determined Aha1 to be an important co-chaperone whose binding to Hsp90 is modulated by phosphorylation, acetylation and SUMOylation of ... [more]
Data Brief Dec. 01, 2015; 5(0);752-5 [Pubmed: 26693507]
Throughput
- High Throughput
Curated By
- BioGRID