BAIT
LRPPRC
CLONE-23970, GP130, LRP130, LSFC
leucine-rich pentatricopeptide repeat containing
GO Process (1)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CENPE
CENP-E, KIF10, MCPH13, PPP1R61
centromere protein E, 312kDa
GO Process (12)
GO Function (4)
GO Component (14)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- attachment of mitotic spindle microtubules to kinetochore [IMP]
- blood coagulation [TAS]
- kinetochore assembly [NAS]
- metabolic process [IMP]
- microtubule-based movement [IBA, TAS]
- mitotic cell cycle [IBA, TAS]
- mitotic chromosome movement towards spindle pole [TAS]
- mitotic metaphase plate congression [IMP]
- positive regulation of protein kinase activity [IMP]
- regulation of mitotic metaphase/anaphase transition [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- chromosome [IDA]
- chromosome, centromeric region [IDA]
- condensed chromosome outer kinetochore [TAS]
- condensed chromosome, centromeric region [IDA]
- cytoplasm [IDA]
- cytosol [TAS]
- kinesin complex [IBA]
- kinetochore [IDA]
- membrane [IDA]
- microtubule [IDA]
- microtubule cytoskeleton [IDA]
- midbody [IDA]
- mitotic spindle midzone [IDA]
- nucleus [IMP]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID