BAIT
KIF2A
CDCBM3, HK2, KIF2
kinesin heavy chain member 2A
GO Process (9)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- blood coagulation [TAS]
- metabolic process [IBA, TAS]
- microtubule depolymerization [IBA]
- microtubule-based movement [IBA, TAS]
- mitotic cell cycle [TAS]
- mitotic spindle organization [IDA]
- spindle assembly involved in mitosis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MTRR
MSR, cblE
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
GO Process (12)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- DNA methylation [ISS]
- cellular nitrogen compound metabolic process [TAS]
- cobalamin metabolic process [TAS]
- folic acid metabolic process [ISS]
- methionine metabolic process [TAS]
- methylation [TAS]
- oxidation-reduction process [TAS]
- small molecule metabolic process [TAS]
- sulfur amino acid metabolic process [TAS]
- vitamin metabolic process [TAS]
- water-soluble vitamin metabolic process [TAS]
- xenobiotic metabolic process [TAS]
Gene Ontology Molecular Function- FMN binding [TAS]
- NADP binding [TAS]
- NADPH-hemoprotein reductase activity [IBA]
- [methionine synthase] reductase activity [TAS]
- flavin adenine dinucleotide binding [IDA, TAS]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [IBA]
- oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [IDA]
- FMN binding [TAS]
- NADP binding [TAS]
- NADPH-hemoprotein reductase activity [IBA]
- [methionine synthase] reductase activity [TAS]
- flavin adenine dinucleotide binding [IDA, TAS]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [IBA]
- oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [IDA]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID