BAIT
KIF2C
CT139, KNSL6, MCAK, RP11-269F19.1
kinesin family member 2C
GO Process (12)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- blood coagulation [TAS]
- cell proliferation [TAS]
- establishment or maintenance of microtubule cytoskeleton polarity [IMP]
- metabolic process [IBA, TAS]
- microtubule depolymerization [IDA, IMP]
- microtubule-based movement [IBA, TAS]
- mitotic cell cycle [TAS]
- mitotic metaphase plate congression [IMP]
- mitotic nuclear division [TAS]
- regulation of chromosome segregation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ADAM9
CORD9, MCMP, MDC9, Mltng
ADAM metallopeptidase domain 9
GO Process (25)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
- PMA-inducible membrane protein ectodomain proteolysis [IDA, TAS]
- activation of MAPKK activity [IDA]
- cell adhesion [IMP]
- cell adhesion mediated by integrin [IMP]
- cell-cell adhesion mediated by integrin [IEP]
- cell-matrix adhesion [IMP]
- cellular response to lipopolysaccharide [IMP]
- collagen catabolic process [TAS]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- integrin-mediated signaling pathway [IC]
- keratinocyte differentiation [IEP]
- membrane protein ectodomain proteolysis [IDA, IMP]
- monocyte activation [IMP]
- positive regulation of cell adhesion mediated by integrin [IMP]
- positive regulation of keratinocyte migration [IMP]
- positive regulation of macrophage fusion [IMP]
- positive regulation of membrane protein ectodomain proteolysis [ISS]
- positive regulation of protein secretion [IDA]
- response to calcium ion [IMP]
- response to glucocorticoid [ISS]
- response to hydrogen peroxide [IMP]
- response to manganese ion [IMP]
- response to tumor necrosis factor [IDA]
- transforming growth factor beta receptor signaling pathway [IMP, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID