BAIT
ZWINT
HZwint-1, KNTC2AP, ZWINT1
ZW10 interacting kinetochore protein
GO Process (4)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
EIF2B3
EIF-2B, EIF2Bgamma, RP5-882O7.2
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
GO Process (11)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- cellular protein metabolic process [TAS]
- cellular response to stimulus [IDA]
- gene expression [TAS]
- negative regulation of translational initiation in response to stress [ISS]
- oligodendrocyte development [IMP]
- positive regulation of GTPase activity [IDA, IMP]
- response to glucose [ISS]
- response to heat [ISS, TAS]
- response to peptide hormone [ISS]
- translation [TAS]
- translational initiation [IDA, TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID