BAIT
ATP6AP2
APT6M8-9, ATP6IP2, ATP6M8-9, ELDF10, M8-9, MRXE, MRXSH, MSTP009, PRR, RENR, XMRE, XPDS, HT028
ATPase, H+ transporting, lysosomal accessory protein 2
GO Process (9)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- angiotensin maturation [IDA, TAS]
- cellular protein metabolic process [TAS]
- eye pigmentation [IMP]
- head morphogenesis [IMP]
- positive regulation of Wnt signaling pathway [IMP]
- positive regulation of transforming growth factor beta1 production [IDA]
- proteolysis [EXP]
- regulation of MAPK cascade [IDA]
- rostrocaudal neural tube patterning [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LAMTOR5
HBXIP, XIP
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
GO Process (8)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- cellular response to amino acid stimulus [IMP]
- negative regulation of apoptotic process [IDA]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- positive regulation of GTPase activity [IDA]
- positive regulation of TOR signaling [IMP]
- protein localization to lysosome [IMP]
- regulation of cell size [IMP]
- response to virus [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID