BAIT
CRY1
AU020726, AU021000, Phll1
cryptochrome 1 (photolyase-like)
GO Process (18)
GO Function (12)
GO Component (2)
Gene Ontology Biological Process
- DNA damage induced protein phosphorylation [IDA]
- circadian regulation of gene expression [IGI, IMP]
- circadian rhythm [IDA, IMP]
- entrainment of circadian clock by photoperiod [IMP]
- gluconeogenesis [IMP]
- glucose homeostasis [IGI]
- lipid storage [IGI]
- negative regulation of G-protein coupled receptor protein signaling pathway [IMP]
- negative regulation of circadian rhythm [IDA, IMP]
- negative regulation of glucocorticoid receptor signaling pathway [IDA, IGI]
- negative regulation of glucocorticoid secretion [IGI]
- negative regulation of protein ubiquitination [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IMP, ISO]
- negative regulation of transcription, DNA-templated [IDA, IGI, ISO]
- regulation of DNA damage checkpoint [IDA]
- regulation of circadian rhythm [IMP]
- response to glucagon [IMP]
- response to insulin [IGI]
Gene Ontology Molecular Function- core promoter binding [IDA]
- core promoter sequence-specific DNA binding [IDA]
- double-stranded DNA binding [IDA, ISO]
- histone deacetylase binding [IPI]
- kinase binding [IPI]
- nuclear hormone receptor binding [IPI, ISO]
- phosphatase binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- transcription factor binding [IPI]
- transcription factor binding transcription factor activity [ISO]
- ubiquitin binding [IDA]
- core promoter binding [IDA]
- core promoter sequence-specific DNA binding [IDA]
- double-stranded DNA binding [IDA, ISO]
- histone deacetylase binding [IPI]
- kinase binding [IPI]
- nuclear hormone receptor binding [IPI, ISO]
- phosphatase binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- transcription factor binding [IPI]
- transcription factor binding transcription factor activity [ISO]
- ubiquitin binding [IDA]
Gene Ontology Cellular Component
Mus musculus
PREY
TAGLN2
HA1756, RP11-48O20.1
transgelin 2
GO Process (1)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID