BAIT
FOXC2
FKHL14, LD, MFH-1, MFH1
forkhead box C2
GO Process (13)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
- heart development [IMP]
- insulin receptor signaling pathway [IDA]
- lymphangiogenesis [IMP]
- mesoderm development [NAS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of cell adhesion mediated by integrin [ISS]
- positive regulation of cell migration involved in sprouting angiogenesis [ISS]
- positive regulation of endothelial cell migration [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of transcription, DNA-templated [IDA]
- positive regulation of vascular wound healing [ISS]
- regulation of transcription from RNA polymerase II promoter [IBA]
- response to hormone [IDA]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin DNA binding [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription regulatory region DNA binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin DNA binding [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription regulatory region DNA binding [ISS]
Homo sapiens
PREY
POU2F2
OCT2, OTF2, Oct-2
POU class 2 homeobox 2
GO Process (2)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]
Mol. Syst. Biol. Jan. 01, 2015; 11(1);775 [Pubmed: 25609649]
Throughput
- High Throughput
Additional Notes
- High-confidence interactions
Curated By
- BioGRID