BAIT
KPNA2
2410044B12Rik, IPOA1, PTAC58, Rch1, RP23-170A23.5
karyopherin (importin) alpha 2
GO Process (2)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell [IDA]
- cytoplasm [ISO]
- intracellular [IDA]
- membrane [ISO]
- nucleoplasm [ISO]
Mus musculus
PREY
SART3
DSAP1, P100, RP11-13G14, TIP110, p110, p110(nrb)
squamous cell carcinoma antigen recognized by T cells 3
GO Process (6)
GO Function (7)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-crystal Structure
Interaction directly demonstrated at the atomic level by X-ray crystallography. Also used for NMR or Electron Microscopy (EM) structures. If there is no obvious bait-hit directionality to the interaction involving 3 or more proteins, then the co-crystallized proteins should be listed as a complex.
Publication
Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3.
Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) is a U4/U6 recycling factor as well as a targeting factor of USP4 and USP15. However, the details of how SART3 recognizes these deubiquitinases and how they get subsequently translocated into the nucleus are not known. Here, we present the crystal structures of the SART3 half-a-tetratricopeptide (HAT) repeat domain alone and ... [more]
Nucleic Acids Res. Apr. 07, 2016; 0(0); [Pubmed: 27060135]
Throughput
- Low Throughput
Curated By
- BioGRID