BAIT
FGFR2
BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
fibroblast growth factor receptor 2
GO Process (96)
GO Function (5)
GO Component (12)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- angiogenesis [ISS]
- axonogenesis [ISS]
- bone development [ISS]
- bone mineralization [ISS]
- bone morphogenesis [ISS]
- branch elongation involved in salivary gland morphogenesis [ISS]
- branching involved in labyrinthine layer morphogenesis [ISS]
- branching involved in prostate gland morphogenesis [ISS]
- branching involved in salivary gland morphogenesis [ISS]
- branching morphogenesis of a nerve [ISS]
- bud elongation involved in lung branching [ISS]
- cell fate commitment [ISS]
- cell-cell signaling [ISS]
- digestive tract development [ISS]
- embryonic cranial skeleton morphogenesis [IMP]
- embryonic digestive tract morphogenesis [ISS]
- embryonic organ development [ISS]
- embryonic organ morphogenesis [ISS]
- embryonic pattern specification [ISS]
- epidermal growth factor receptor signaling pathway [TAS]
- epidermis morphogenesis [ISS]
- epithelial cell differentiation [ISS]
- epithelial cell proliferation involved in salivary gland morphogenesis [ISS]
- fibroblast growth factor receptor signaling pathway [IDA, IGI, IPI, TAS]
- fibroblast growth factor receptor signaling pathway involved in hemopoiesis [ISS]
- fibroblast growth factor receptor signaling pathway involved in mammary gland specification [ISS]
- fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow [ISS]
- fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [ISS]
- fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [ISS]
- gland morphogenesis [ISS]
- hair follicle morphogenesis [ISS]
- in utero embryonic development [ISS]
- innate immune response [TAS]
- inner ear morphogenesis [ISS]
- insulin receptor signaling pathway [TAS]
- lacrimal gland development [ISS]
- lateral sprouting from an epithelium [ISS]
- limb bud formation [ISS]
- lung alveolus development [ISS]
- lung development [ISS]
- lung lobe morphogenesis [ISS]
- lung-associated mesenchyme development [ISS]
- mammary gland bud formation [ISS]
- membranous septum morphogenesis [ISS]
- mesenchymal cell differentiation [ISS]
- mesenchymal cell differentiation involved in lung development [ISS]
- mesenchymal cell proliferation involved in lung development [ISS]
- midbrain development [ISS]
- morphogenesis of embryonic epithelium [ISS]
- multicellular organism growth [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- neurotrophin TRK receptor signaling pathway [TAS]
- odontogenesis [ISS]
- orbitofrontal cortex development [ISS]
- organ growth [ISS]
- organ morphogenesis [ISS]
- otic vesicle formation [ISS]
- outflow tract septum morphogenesis [ISS]
- peptidyl-tyrosine phosphorylation [IDA]
- phosphatidylinositol-mediated signaling [TAS]
- positive regulation of ERK1 and ERK2 cascade [ISS]
- positive regulation of MAPK cascade [IMP]
- positive regulation of Wnt signaling pathway [ISS]
- positive regulation of canonical Wnt signaling pathway [ISS]
- positive regulation of cardiac muscle cell proliferation [ISS]
- positive regulation of cell cycle [ISS]
- positive regulation of cell division [ISS]
- positive regulation of cell proliferation [IDA, IGI, IMP]
- positive regulation of epithelial cell proliferation [ISS]
- positive regulation of epithelial cell proliferation involved in lung morphogenesis [ISS]
- positive regulation of mesenchymal cell proliferation [ISS]
- positive regulation of phospholipase activity [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- post-embryonic development [ISS]
- prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [ISS]
- prostate epithelial cord elongation [ISS]
- prostate gland morphogenesis [ISS]
- protein autophosphorylation [IDA]
- pyramidal neuron development [ISS]
- regulation of ERK1 and ERK2 cascade [ISS]
- regulation of branching involved in prostate gland morphogenesis [ISS]
- regulation of cell fate commitment [ISS]
- regulation of fibroblast growth factor receptor signaling pathway [ISS]
- regulation of morphogenesis of a branching structure [ISS]
- regulation of multicellular organism growth [ISS]
- regulation of osteoblast differentiation [TAS]
- regulation of osteoblast proliferation [TAS]
- regulation of smooth muscle cell differentiation [ISS]
- regulation of smoothened signaling pathway [ISS]
- reproductive structure development [ISS]
- skeletal system morphogenesis [TAS]
- squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [ISS]
- ureteric bud development [ISS]
- ventricular cardiac muscle tissue morphogenesis [ISS]
- ventricular zone neuroblast division [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
FGF3
HBGF-3, INT2
fibroblast growth factor 3
GO Process (12)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- anatomical structure morphogenesis [TAS]
- cell-cell signaling [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [IGI, TAS]
- innate immune response [TAS]
- insulin receptor signaling pathway [TAS]
- negative regulation of cardiac muscle tissue development [IMP]
- neurotrophin TRK receptor signaling pathway [TAS]
- phosphatidylinositol-mediated signaling [TAS]
- positive regulation of cell proliferation [IGI]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Fibroblast growth factor-derived peptides: functional agonists of the fibroblast growth factor receptor.
A series of peptides, termed dekafins, were derived from the beta10-beta11 loop regions of fibroblast growth factors (FGFs) 1, 2, 3, 5, 6, 8, 9, 10, and 17. The dekafins share a homologous amino acid sequence similar to a sequence in the first fibronectin type III module of the neural cell adhesion molecule. All dekafins were shown by surface plasmon ... [more]
J. Neurochem. Feb. 01, 2008; 104(3);667-82 [Pubmed: 18199118]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| FGF3 FGFR2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9211 | BioGRID | 3288392 |
Curated By
- BioGRID