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BAIT

SLC4A1

AE1, BND3, CD233, DI, EMPB3, EPB3, FR, RTA1A, SW, WD, WD1, WR

solute carrier family 4 (anion exchanger), member 1 (Diego blood group)

GO Process (7)

GO Function (9)

GO Component (8)

Gene Ontology Biological Process

anion transport [IDA]

bicarbonate transport [IDA, TAS]

cellular ion homeostasis [TAS]

chloride transport [ISS]

ion transport [TAS]

small molecule metabolic process [TAS]

transmembrane transport [TAS]

Gene Ontology Molecular Function

anion transmembrane transporter activity [TAS]
anion:anion antiporter activity [IDA]
ankyrin binding [IPI]
bicarbonate transmembrane transporter activity [IDA]
chloride transmembrane transporter activity [ISS]
inorganic anion exchanger activity [IDA, TAS]
protein anchor [TAS]
protein binding [IPI]
protein homodimerization activity [IPI]

Gene Ontology Cellular Component

basolateral plasma membrane [IDA]

blood microparticle [IDA]

cortical cytoskeleton [IDA]

extracellular vesicular exosome [IDA]

integral component of membrane [NAS]

integral component of plasma membrane [IDA]

plasma membrane [TAS]

CRISPR Database HGNC Alliance of Genome Resources VEGA OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

SLC4A1AP

HLC3

solute carrier family 4 (anion exchanger), member 1, adaptor protein

GO Process (0)

GO Function (1)

GO Component (4)

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

intracellular membrane-bounded organelle [IDA]

nucleoplasm [IDA]

plasma membrane [IDA]

CRISPR Database VEGA HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Kanadaptin is a protein that interacts with the kidney but not the erythroid form of band 3.

Chen J, Vijayakumar S, Li X, Al-Awqati Q

Although epithelial membrane proteins are separately targeted to apical or basolateral domains, some are apically located in one cell type but are basolateral in others. More dramatically, the anion exchanger of a clonal cell line of intercalated cells derived from the kidney can be retargeted from the apical to basolateral domain. This Cl:HCO3 exchanger, kAE1, is an alternately spliced form ... [more]

J. Biol. Chem. Jan. 09, 1998; 273(2);1038-43 [Pubmed: 9422766]

Throughput

Low Throughput

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
SLC4A1AP SLC4A1	Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro.	Chen J (1998)	Low	-	BioGRID	-

Curated By

BioGRID