BAIT
SLC4A1AP
HLC3
solute carrier family 4 (anion exchanger), member 1, adaptor protein
GO Process (0)
GO Function (1)
GO Component (4)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC4A1
AE1, BND3, CD233, DI, EMPB3, EPB3, FR, RTA1A, SW, WD, WD1, WR
solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
GO Process (7)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function- anion transmembrane transporter activity [TAS]
- anion:anion antiporter activity [IDA]
- ankyrin binding [IPI]
- bicarbonate transmembrane transporter activity [IDA]
- chloride transmembrane transporter activity [ISS]
- inorganic anion exchanger activity [IDA, TAS]
- protein anchor [TAS]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- anion transmembrane transporter activity [TAS]
- anion:anion antiporter activity [IDA]
- ankyrin binding [IPI]
- bicarbonate transmembrane transporter activity [IDA]
- chloride transmembrane transporter activity [ISS]
- inorganic anion exchanger activity [IDA, TAS]
- protein anchor [TAS]
- protein binding [IPI]
- protein homodimerization activity [IPI]
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Kanadaptin is a protein that interacts with the kidney but not the erythroid form of band 3.
Although epithelial membrane proteins are separately targeted to apical or basolateral domains, some are apically located in one cell type but are basolateral in others. More dramatically, the anion exchanger of a clonal cell line of intercalated cells derived from the kidney can be retargeted from the apical to basolateral domain. This Cl:HCO3 exchanger, kAE1, is an alternately spliced form ... [more]
J. Biol. Chem. Jan. 09, 1998; 273(2);1038-43 [Pubmed: 9422766]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SLC4A1 SLC4A1AP | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID