RPB3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ADR1
Gene Ontology Biological Process
- cellular response to oleic acid [IPI]
- chromatin organization [IDA]
- chromatin organization involved in regulation of transcription [IGI, IMP, IPI]
- negative regulation of chromatin silencing [IDA]
- peroxisome organization [IMP]
- positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of fatty acid beta-oxidation by positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of peroxisome organization by positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription from RNA polymerase II promoter by oleic acid [IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to ethanol [IMP]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IPI]
- TFIIB-class transcription factor binding [IDA]
- TFIID-class transcription factor binding [IDA]
- sequence-specific DNA binding [IDA]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IPI]
- TFIIB-class transcription factor binding [IDA]
- TFIID-class transcription factor binding [IDA]
- sequence-specific DNA binding [IDA]
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Subgenic Pol II interactomes identify region-specific transcription elongation regulators.
Transcription, RNA processing, and chromatin-related factors all interact with RNA polymerase II (Pol II) to ensure proper timing and coordination of transcription and co-transcriptional processes. Many transcription elongation regulators must function simultaneously to coordinate these processes, yet few strategies exist to explore the complement of factors regulating specific stages of transcription. To this end, we developed a strategy to purify ... [more]
Throughput
- High Throughput
Additional Notes
- 3' PolII enriched factors
- 5' PolII enriched factors
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
ADR1 RPB3 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -4.8054 | BioGRID | 508226 |
Curated By
- BioGRID