BAIT
CBR1
CBR, SDR21C1, hCBR1
carbonyl reductase 1
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
CBR1
CBR, SDR21C1, hCBR1
carbonyl reductase 1
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Co-crystal Structure
Interaction directly demonstrated at the atomic level by X-ray crystallography. Also used for NMR or Electron Microscopy (EM) structures. If there is no obvious bait-hit directionality to the interaction involving 3 or more proteins, then the co-crystallized proteins should be listed as a complex.
Publication
Structural insights on the catalytic site protection of human carbonyl reductase 1 by glutathione.
The NADPH-dependent human carbonyl reductase 1 (hCBR1), a member of the short-chain dehydrogenase/reductase protein family, plays an important role in the ubiquitous metabolism of endogenous and xenobiotic carbonyl containing compounds. Glutathione (GSH) is also a cofactor of hCBR1, however, its role in the carbonyl reductase function of the enzyme is still unclear. In this study, we presented the crystal structure ... [more]
J. Struct. Biol. Oct. 01, 2015; 192(1);138-44 [Pubmed: 26381805]
Throughput
- Low Throughput
Curated By
- BioGRID