FOXJ1
Gene Ontology Biological Process
- actin cytoskeleton organization [ISS]
- activation of Rho GTPase activity [ISS]
- brain development [ISS, NAS]
- central tolerance induction [ISS]
- cilium assembly [ISS]
- cilium morphogenesis [ISS]
- epithelium development [ISS]
- establishment of apical/basal cell polarity [ISS]
- glomerular parietal epithelial cell development [IEP]
- humoral immune response [ISS]
- leukocyte migration [ISS]
- lung epithelium development [IEP, NAS]
- metanephric part of ureteric bud development [IEP]
- negative regulation of B cell activation [ISS]
- negative regulation of NF-kappaB transcription factor activity [ISS]
- negative regulation of T cell differentiation in thymus [ISS]
- negative regulation of germinal center formation [ISS]
- negative regulation of humoral immune response mediated by circulating immunoglobulin [ISS]
- negative regulation of interleukin-6 biosynthetic process [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- pattern specification process [ISS]
- positive regulation of central B cell tolerance induction [ISS]
- positive regulation of lung ciliated cell differentiation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- spermatogenesis [NAS]
- transcription from RNA polymerase II promoter [IBA]
Gene Ontology Molecular Function
RFX1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Quantitative Score
- 0.99999995 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.99999995, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| FOXJ1 RFX1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3035422 | |
| FOXJ1 RFX1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 1507575 |
Curated By
- BioGRID