BAIT
SPTAN1
EIEE5, NEAS, SPTA2
spectrin, alpha, non-erythrocytic 1
GO Process (3)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KALRN
ARHGEF24, CHD5, CHDS5, DUET, DUO, HAPIP, TRAD, RP11-71H17.7
kalirin, RhoGEF kinase
GO Process (10)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- apoptotic signaling pathway [TAS]
- intracellular signal transduction [ISS]
- nervous system development [ISS]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of GTPase activity [TAS]
- positive regulation of apoptotic process [TAS]
- regulation of small GTPase mediated signal transduction [TAS]
- signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
- vesicle-mediated transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.
The N-terminal region of non-erythroid alpha spectrin (Sp alpha II) is responsible for interacting with its binding partner, beta spectrin, to form functional spectrin tetramers. We used a yeast-two-hybrid system, with an N-terminal segment of alpha spectrin representing the functional tetramerization site, as a bait to screen human brain c-DNA library for proteins that interact with the alpha spectrin segment. ... [more]
Cell. Mol. Biol. Lett. Jul. 04, 2007; 12(4);604-20 [Pubmed: 17607528]
Throughput
- Low Throughput
Curated By
- BioGRID