LOLAL
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RIB
Gene Ontology Biological Process
- Malpighian tubule morphogenesis [IMP]
- cell migration [TAS]
- central nervous system development [IMP]
- cytoskeleton organization [TAS]
- dorsal closure [IMP, NAS, TAS]
- epithelial cell migration, open tracheal system [IMP]
- establishment or maintenance of epithelial cell apical/basal polarity [IMP]
- gonad development [IMP]
- head involution [IMP]
- hindgut morphogenesis [IMP]
- lumen formation, open tracheal system [TAS]
- membrane organization [TAS]
- open tracheal system development [IMP, NAS, TAS]
- primary branching, open tracheal system [TAS]
- protein localization [IMP]
- regulation of Malpighian tubule diameter [IMP]
- regulation of cell shape [IMP, TAS]
- regulation of transcription, DNA-templated [TAS]
- salivary gland development [TAS]
- salivary gland morphogenesis [IMP, NAS]
- tracheal outgrowth, open tracheal system [IMP]
Gene Ontology Molecular Function
Phenotypic Enhancement
A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
Ribbon modulates apical membrane during tube elongation through Crumbs and Moesin.
Although the formation and maintenance of epithelial tubes are essential for the viability of multicellular organisms, our understanding of the molecular and cellular events coordinating tubulogenesis is relatively limited. Here, we focus on the activities of Ribbon, a novel BTB-domain containing nuclear protein, in the elongation of two epithelial tubes: the Drosophila salivary gland and trachea. We show that Ribbon ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RIB LOLAL | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
| LOLAL RIB | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |