RIB
Gene Ontology Biological Process
- Malpighian tubule morphogenesis [IMP]
- cell migration [TAS]
- central nervous system development [IMP]
- cytoskeleton organization [TAS]
- dorsal closure [IMP, NAS, TAS]
- epithelial cell migration, open tracheal system [IMP]
- establishment or maintenance of epithelial cell apical/basal polarity [IMP]
- gonad development [IMP]
- head involution [IMP]
- hindgut morphogenesis [IMP]
- lumen formation, open tracheal system [TAS]
- membrane organization [TAS]
- open tracheal system development [IMP, NAS, TAS]
- primary branching, open tracheal system [TAS]
- protein localization [IMP]
- regulation of Malpighian tubule diameter [IMP]
- regulation of cell shape [IMP, TAS]
- regulation of transcription, DNA-templated [TAS]
- salivary gland development [TAS]
- salivary gland morphogenesis [IMP, NAS]
- tracheal outgrowth, open tracheal system [IMP]
Gene Ontology Molecular Function
LOLAL
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein complex network of Drosophila melanogaster.
Determining the composition of protein complexes is an essential step toward understanding the cell as an integrated system. Using coaffinity purification coupled to mass spectrometry analysis, we examined protein associations involving nearly 5,000 individual, FLAG-HA epitope-tagged Drosophila proteins. Stringent analysis of these data, based on a statistical framework designed to define individual protein-protein interactions, led to the generation of a ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
LOLAL RIB | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - | |
LOLAL RIB | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID