STMN2
Gene Ontology Biological Process
- cellular response to nerve growth factor stimulus [IDA]
- negative regulation of microtubule depolymerization [IDA]
- negative regulation of microtubule polymerization [IDA]
- negative regulation of neuron projection development [IDA]
- positive regulation of microtubule depolymerization [IDA]
- positive regulation of neuron projection development [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
FANCC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
The Fanconi Anemia C Protein Binds to and Regulates Stathmin-1 Phosphorylation.
The Fanconi anemia (FA) proteins are involved in a signaling network that assures the safeguard of chromosomes. To understand the function of FA proteins in cellular division events, we investigated the interaction between Stathmin-1 (STMN1) and the FA group C (FANCC) protein. STMN1 is a ubiquitous cytosolic protein that regulates microtubule dynamics. STMN1 activities are regulated through phosphorylation-dephosphorylation mechanisms that ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| FANCC STMN2 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID