Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The Fanconi anemia group C protein interacts with uncoordinated 5A and delays apoptosis.

Huang F, Ben Aissa M, Magron A, Huard CC, Godin C, Levesque G, Carreau M

The Fanconi anemia group C protein (FANCC) is one of the several proteins that comprise the Fanconi anemia (FA) network involved in genomic surveillance. FANCC is mainly cytoplasmic and has many functions, including apoptosis suppression through caspase-mediated proteolytic processing. Here, we examined the role of FANCC proteolytic fragments by identifying their binding partners. We performed a yeast two-hybrid screen with ... [more]

PLoS ONE Mar. 29, 2014; 9(3);e92811 [Pubmed: 24676280]

Throughput

Low Throughput

Curated By

BioGRID

Interaction Summary

FANCC

Gene Ontology Biological Process

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

CCNA2