BAIT
FANCC
FA3, FAC, FACC, RP11-80I15.2
Fanconi anemia, complementation group C
GO Process (2)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CCNA2
CCN1, CCNA
cyclin A2
GO Process (4)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
The Fanconi anemia group C protein interacts with uncoordinated 5A and delays apoptosis.
The Fanconi anemia group C protein (FANCC) is one of the several proteins that comprise the Fanconi anemia (FA) network involved in genomic surveillance. FANCC is mainly cytoplasmic and has many functions, including apoptosis suppression through caspase-mediated proteolytic processing. Here, we examined the role of FANCC proteolytic fragments by identifying their binding partners. We performed a yeast two-hybrid screen with ... [more]
PLoS ONE Mar. 29, 2014; 9(3);e92811 [Pubmed: 24676280]
Throughput
- Low Throughput
Curated By
- BioGRID