BAIT
ORF21
HHV8GK18_gp25
thymidine kinase
GO Process (0)
GO Function (0)
GO Component (0)
Human Herpesvirus 8
PREY
CDC23
ANAPC8, APC8, CUT23
cell division cycle 23
GO Process (13)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [TAS]
- metaphase/anaphase transition of mitotic cell cycle [TAS]
- mitotic cell cycle [TAS]
- mitotic metaphase plate congression [IDA]
- mitotic nuclear division [IDA]
- mitotic spindle assembly checkpoint [TAS]
- negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- protein K11-linked ubiquitination [IDA]
- regulation of exit from mitosis [TAS]
- regulation of mitotic metaphase/anaphase transition [IDA]
- regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- ubiquitin-dependent protein catabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.
Mapping host-pathogen interactions has proven instrumental for understanding how viruses manipulate host machinery and how numerous cellular processes are regulated. DNA viruses such as herpesviruses have relatively large coding capacity and thus can target an extensive network of cellular proteins. To identify the host proteins hijacked by this pathogen, we systematically affinity tagged and purified all 89 proteins of Kaposi's ... [more]
Mol. Cell Jan. 22, 2015; 57(2);349-60 [Pubmed: 25544563]
Throughput
- High Throughput
Curated By
- BioGRID