BAIT
HNRNPC
C1, C2, HNRNP, HNRPC, SNRPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
GO Process (6)
GO Function (9)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function- RNA binding [NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- identical protein binding [IPI]
- mRNA 3'-UTR binding [IDA]
- nucleosomal DNA binding [IDA]
- poly(A) RNA binding [IDA]
- poly(U) RNA binding [IDA]
- protein binding [IPI]
- RNA binding [NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- identical protein binding [IPI]
- mRNA 3'-UTR binding [IDA]
- nucleosomal DNA binding [IDA]
- poly(A) RNA binding [IDA]
- poly(U) RNA binding [IDA]
- protein binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
PREY
TRAF3
CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1
TNF receptor-associated factor 3
GO Process (14)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- MyD88-independent toll-like receptor signaling pathway [TAS]
- TRIF-dependent toll-like receptor signaling pathway [TAS]
- innate immune response [TAS]
- negative regulation of NF-kappaB transcription factor activity [IMP]
- negative regulation of type I interferon production [TAS]
- regulation of cytokine production [ISS]
- regulation of defense response to virus [ISS]
- regulation of interferon-beta production [ISS]
- regulation of proteolysis [IMP]
- signal transduction [TAS]
- toll-like receptor 3 signaling pathway [TAS]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor signaling pathway [ISS, TAS]
- tumor necrosis factor-mediated signaling pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
Activation-Dependent TRAF3 Exon 8 Alternative Splicing Is Controlled by CELF2 and hnRNP C Binding to an Upstream Intronic Element.
Cell-type-specific and inducible alternative splicing has a fundamental impact on regulating gene expression and cellular function in a variety of settings, including activation and differentiation. We have recently shown that activation-induced skipping of TRAF3 exon 8 activates noncanonical NF-κB signaling upon T cell stimulation, but the regulatory basis for this splicing event remains unknown. Here we identifycis- andtrans-regulatory elements rendering ... [more]
Mol. Cell. Biol. Apr. 01, 2017; 37(7); [Pubmed: 28031331]
Throughput
- Low Throughput
Additional Notes
- protein(s) IPd from lysate with anti-HNRNPC antibody interact with (i.e. likely are a) binding partner of RNA of TRAF3 exon8
Curated By
- BioGRID